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No. 1 North Carolina Favored Over No. 5 Indiana in Sweet Sixteen

Let's take a look at Friday night's NCAA Sweet Sixteen matchup between the No. 5 Indiana Hoosiers and the No. 1 North Carolina Tar Heels. The game at the Wells Fargo Center in Philadelphia, PA, is scheduled to tip off at 9:55 PM ET. Currently, UNC is favored to win this East Regional Semifinals matchup.

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The Hoosiers are 27-7 SU and 19-15 ATS so far this season. Sixteen of their games have gone OVER the line, with the other eighteen all going UNDER. They are coming off of a 73-67 win over the Kentucky Wildcats, where they won against the spread as 3 ½ point underdogs. The total went UNDER the 157 point line set by sports gambling oddsmakers in that matchup.

The Tar Heels are 30-6 SU and 17-18-1 ATS overall this year. Eighteen of their games have gone OVER the line, with the other eighteen all going UNDER. They are coming off of an 85-66 win over the Providence Friars, where they won against the spread as -11 point favorites. The total went UNDER the 152 point line set by NCAA basketball gambling experts for that game.

Indiana is 6-1 ATS in non-conference play, and 5-1 ATS overall lately. They are 4-1 ATS coming off of a SU win, and 4-1 ATS against teams with a winning record. They are 12-26 ATS coming off of a win spreadwise, and 2-5 ATS against ACC opponents.

The total has gone UNDER in 4 of their last 5 games coming off of a SU win, and UNDER in 4 of their last 5 games at a neutral site. The total has gone OVER in 20 of their last 28 games against non-conference teams, and OVER in 12 of their last 17 games on Friday.

North Carolina is 4-0 ATS on Friday night, and 5-1 ATS coming off of a SU win. They are 5-1 ATS against teams with a winning record overall, and 5-1 ATS when playing at a neutral site. They are 5-1 ATS overall recently, and 2-6 ATS in the NCAA tournament.

The total has gone OVER in 6 of their last 7 games against non-conference opponents, and UNDER in 14 of their last 19 games overall. The total has gone UNDER in 8 of their last 11 against Big Ten opponents, and OVER in 5 of their last 7 games on Friday. The total has gone OVER in 5 of their last 7 games in the NCAA tournament, and OVER in 21 of their last 31 at a neutral site.

Between these teams, Indiana is 4-0 ATS lately.

They last met in November 2012, when Indiana won 83-59, and covered the spread as -11 point home favorites. The total went UNDER the 149 ½ point line set by sportsbook oddsmakers in that matchup.

For Friday night's matchup, gambling odds list the Tar Heels as -5 ½ point favorites. The over/under is set at 158 ½ points. On the moneyline, Indiana is listed at +205, with North Carolina a -245.