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NFL Betting: Buffalo Bills vs. Jacksonville Jaguars

On Sunday, the Bills (1-0, 1-0 ATS) head down to the Sunshine State to take on the Jaguars (0-1, 0-1 ATS) for an NFL betting match-up.

This NFL betting matchup is slated to kick from Jacksonville Municipal Stadium at 1:00 ET. The Bills will be in search of some payback, as last year they got crushed by the Jags 36-14 as nine-point underdogs. All of a sudden, there’s hope in Buffalo that the Bills could be serious contenders to the AFC East crown.

With the Patriots having to deal without QB Tom Brady for the rest of the season, Buffalo’s football betting odds have plummeted to win the division. They also looked great for their NFL betting fans on Sunday afternoon, knocking off the Seahawks 34-10 as short favorites in their home opener.

The Bills pass defense was fantastic in Week 1, holding Seattle QB Matt Hasselbeck to just 190 yards on 17 of 41 pass attempts. They should get a better test from the Jags balanced offense this week. Even though expectations are high for HC Jack Del Rio and the Jags in ’08, their season opened with a thud for their football betting followers in Week 1.

Jacksonville had the edge on the NFL betting line, getting the nod from the oddsmakers by three-points, but they never really stood much of a chance against a very well-rounded Tennessee squad. QB David Garrard had a very uncharacteristic sloppy performance, and threw a pair of interceptions; he only had three picks all of last season.

The news is even worse for the offensive line, which will now have to do without offensive linemen Vince Manuwai and Maurice Williams for the rest of the season. In spite of the extensive injuries to the Jags, they’re still favored by 5.5-points against the Bills with the ‘total’ in the 37 to 37.5 range.

Keep an eye on the ‘over’ this weekend, as the Jags are 16-5-2 against the ‘over’ in their L/23 games overall. has all of the NFL betting you can sink your teeth into for this and every game on the Week 2 betting slate.

Be sure to open an account right now and get your action down on this AFC clash before the opening kick!