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NFL Betting: Buffalo Bills vs. Arizona Cardinals

The Cardinals (2-2, 2-2 ATS) return to University of Phoenix Stadium to do battle with the Bills (4-0, 3-1 ATS) in an NFL betting affair Sunday afternoon.

Kick-off from the desert is set for 4:15 ET. These teams don’t hook up often, but the Bills have dominated their L/4 meetings, going 4-0 SU and ATS, and outscoring the Cards by an average of 18 ppg. Short of a dud against Oakland two weeks ago, football betting aficionados that have backed the Bills have turned a healthy profit.

The NFL odds were stacked against Buffalo on Sunday afternoon, as the Rams came out of the blocks fired up even though they were 9.5-point underdogs. At halftime, St. Louis led 14-6, but it was all downhill for the fans at the Edward Jones Dome after that.

Buffalo went on a 25-0 run to close out the game, producing an easy 31-14 win and giving Rams HC Scott Linehan his final walking papers. The defense has been fantastic for Buffalo this season, ranking 5th in the NFL in points per game allowed at just 15.8.

It’s not often that you can throw for 472 yards, have three 100+ yard receivers, and score 35 points in a half of football and lose, but that’s exactly what Arizona pulled off last Sunday against the Jets. The Cardinals defense was miserable, allowing QB Brett Favre to throw for a career-high six touchdown passes.

The 56-35 loss was a shock to the system for NFL betting supporters who wagered on the ‘under’, as the game was scoreless at the end of the first quarter. The Cardinals never had a chance to cover the football betting line.

Arizona will likely be without WR Anquan Boldin this Sunday, as he was carted off the field right at the end of the game after suffering a helmet-to-helmet collision. Arizona has covered six of its L/9 home games, and that’s a trend that NFL betting fans have caught on to.

Oddsmakers originally opened the Bills as 3-point road favorites, but they’re now one-point road underdogs with the ‘total’ penciled in at 45. Don’t miss your chance to sink your teeth into all of the great football betting action this weekend!

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